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PMID: 2895061 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

The anonymous RFLP locus D1S2 is close to PGM1 on chromosome 1.

Human heredity ·Vol. 38 ·No. 1 ·1988-00-00 ·Pages 22-6

Kidd KK, Kidd JR, Castiglione CM, Sparkes RS, Egeland JA, Bakker E

Abstract

D1S2 was one of the first restriction fragment length polymorphisms (RFLPs) assigned to chromosome 1, but its regional location was unknown. In this paper we present data that place this RFLP into both the genetic map and the physical-cytogenetic map. Linkage data maps D1S2 7 cM from PGM1, which is localized to the middle of the short arm at 1p22.1. Southern blot analysis of DNA samples from somatic cell hybrids containing parts of chromosome 1 maps D1S2 proximal to 1p32 and distal to PGM1.

MeSH Terms

Chromosomes, Human, Pair 1 Genetic Linkage Humans Phosphoglucomutase/genetics Polymorphism, Genetic Polymorphism, Restriction Fragment Length

Chemicals

Phosphoglucomutase

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Kidd K K

Department of Human Genetics, Yale University School of Medicine, New Haven, Conn.

Kidd J R

Castiglione C M

Sparkes R S

Egeland J A

Bakker E

Article Info

Journal

Human heredity

Abbr.

Hum Hered

ISSN

0001-5652

DOI

10.1159/000153749

Published

1988-00-00

Pages

22-6

Language

English

Region

Switzerland

NLM ID

0200525

Subset

Grants

NCI NIH HHS · CA32066 · United States

NIMH NIH HHS · MH30929 · United States

NIMH NIH HHS · MH39239 · United States

External Links

PubMed source DOI: 10.1159/000153749 View journal details

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The anonymous RFLP locus D1S2 is close to PGM1 on chromosome 1.

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