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PMID: 2892786 Published · ppublish English Journal Article

Myc-1 is centromeric to the linkage group Ly-6--Sis--Gdc-1 on mouse chromosome 15.

Immunogenetics ·Vol. 27 ·No. 3 ·1988-00-00 ·Pages 215-9

Huppi K, Duncan R, Potter M

Abstract

A survey of wild mouse DNA with a c-myc exon 1 probe revealed a Taq I restriction fragment length polymorphism (RFLP) among Mus species. As a result of this Taq I RFLP, a cross between Mus musculus domesticus and BALB/cJ permitted the positioning of Myc-1 on chromosome 15 with respect to Ly-6, Sis, and Gdc-1. Compilation of the recombination frequency generated from this cross with published cytogenetic and plasma-cytoma somatic cell hybrid data suggests the following chromosome 15 orientation: centromere--Myc-1--Ly-6--Sis--Gdc-1--telomere. This gene order is consistent with conservation of man-mouse synteny.

MeSH Terms
Animals Antigens, Ly/genetics Centromere/analysis Chromosome Mapping Chromosomes/analysis Crosses, Genetic Exons Female Genetic Linkage Male Mice Mice, Inbred BALB C Oncogenes Polymorphism, Restriction Fragment Length Recombination, Genetic
Chemicals
Antigens, Ly
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Huppi K
Laboratory of Genetics, National Cancer Institute, Bethesda, MD 20892.
Duncan R
Potter M
References (21)
21 references, click to expand
  1. Gene localization on sorted chromosomes: definitive evidence on the relative positioning of genes participating in the mouse plasmacytoma-associated typical translocation.
    Proc Natl Acad Sci U S A. 1985 Oct;82(20):6975-9 PMID: 2995997
  2. The contribution of wild derived mouse inbred strains to gene mapping methodology.
    Curr Top Microbiol Immunol. 1986;127:109-13 PMID: 3460738
  3. The c-myc oncogene is translocated to the involved chromosome 12 in mouse plasmacytoma.
    Proc Natl Acad Sci U S A. 1985 Jun;82(12):4212-6 PMID: 3923490
  4. Mouse sn-glycerol-3-phosphate dehydrogenase: molecular cloning and genetic mapping of a cDNA sequence.
    Proc Natl Acad Sci U S A. 1983 May;80(10):3020-4 PMID: 6407006
  5. Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.
    EMBO J. 1983;2(12):2375-83 PMID: 6321164
  6. Nonrandom chromosome changes involving the Ig gene-carrying chromosomes 12 and 6 in pristane-induced mouse plasmacytomas.
    Cell. 1979 Dec;18(4):1001-7 PMID: 519762
  7. The congenital goiter mutation is linked to the thyroglobulin gene in the mouse.
    Proc Natl Acad Sci U S A. 1987 Apr;84(7):1986-90 PMID: 2882514
  8. Clustered somatic mutations in and around first exon of non-rearranged c-myc in Burkitt lymphoma with t(8;22) translocation.
    Nucleic Acids Res. 1987 Jun 11;15(11):4553-65 PMID: 3035497
  9. Igk polymorphism in M. musculus domesticus populations from Maryland and Delaware.
    Curr Top Microbiol Immunol. 1986;127:175-85 PMID: 3089695
  10. Listing of stocks and strains of mice in the genus Mus derived from the feral state.
    Curr Top Microbiol Immunol. 1986;127:373-95 PMID: 3731853
  11. Cytogenetic studies on IgA/lambda-producing murine plasmacytomas: regular occurrence of a T(12;15) translocation.
    Somatic Cell Genet. 1980 Nov;6(6):731-8 PMID: 7444720
  12. Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4.
    Genetics. 1986 Dec;114(4):1239-55 PMID: 3100390
  13. p380-8A 1.8 SaSs, a single copy clone 5' of c-myc at 8q24 which recognizes an SstI polymorphism.
    Nucleic Acids Res. 1987 Jan 26;15(2):865 PMID: 2881266
  14. Activation and somatic mutation of the translocated c-myc gene in burkitt lymphoma cells.
    Cell. 1984 Feb;36(2):339-48 PMID: 6319017
  15. Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas.
    Nature. 1983 Jun 2-8;303(5916):401-6 PMID: 6304522
  16. Assignment of the Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1 region to mouse chromosome 15.
    Immunogenetics. 1987;25(6):361-72 PMID: 2885263
  17. Mapping of the mouse Ly-6, Xp-14, and Gdc-1 loci to chromosome 15.
    Immunogenetics. 1987;25(1):21-7 PMID: 2880797
  18. Murine Ly-6 multigene family is located on chromosome 15.
    Proc Natl Acad Sci U S A. 1987 Mar;84(6):1638-42 PMID: 2882510
  19. Interacting genes control glycerol-3-phosphate dehydrogenase expression in developing cerebellum of the mouse.
    Genetics. 1985 May;110(1):123-43 PMID: 3996895
  20. Mapping of the c-myc, pvt-1 and immunoglobulin kappa genes in relation to the mouse plasmacytoma-associated variant (6;15) translocation breakpoint.
    EMBO J. 1985 Dec 1;4(12):3183-8 PMID: 3937724
  21. Mapping of the oncogenes Myc, Sis, and int-1 to the distal part of mouse chromosome 15.
    Cytogenet Cell Genet. 1987;44(2-3):65-8 PMID: 3471390
Article Info
Journal
Immunogenetics
Abbr.
Immunogenetics
ISSN
0093-7711
DOI
10.1007/BF00346589
Published
1988-00-00
Pages
215-9
Language
English
Region
United States
NLM ID
0420404
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00346589 View journal details
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