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PMID: 2881209 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Bipolar affective disorders linked to DNA markers on chromosome 11.

Nature ·Vol. 325 ·No. 6107 ·1987-00-00 ·Pages 783-7

Egeland JA, Gerhard DS, Pauls DL, Sussex JN, Kidd KK, Allen CR, Hostetter AM, Housman DE

Abstract

An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.

MeSH Terms

Adolescent Adult Bipolar Disorder/epidemiology,ethnology,genetics Christianity Chromosomes, Human, Pair 11 DNA/genetics Ethnicity Genetic Markers Humans Pedigree Pennsylvania Polymorphism, Restriction Fragment Length Religion and Medicine

Chemicals

Genetic Markers DNA

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Egeland J A

Gerhard D S

Pauls D L

Sussex J N

Kidd K K

Allen C R

Hostetter A M

Housman D E

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/325783a0

Published

1987-00-00

Pages

783-7

Language

English

Region

England

NLM ID

0410462

Subset

Grants

NIMH NIH HHS · MH00508 · United States

NIMH NIH HHS · MH28274 · United States

NIMH NIH HHS · MH28287 · United States

External Links

PubMed source DOI: 10.1038/325783a0 View journal details

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Bipolar affective disorders linked to DNA markers on chromosome 11.

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