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PMID: 28710774 Published · ppublish English Journal Article Research Support, N.I.H., Extramural

UCSF ChimeraX: Meeting modern challenges in visualization and analysis.

Protein science : a publication of the Protein Society ·Vol. 27 ·No. 1 ·2018-00-00 ·Pages 14-25

Goddard TD, Huang CC, Meng EC, Pettersen EF, Couch GS, Morris JH, Ferrin TE

Abstract

UCSF ChimeraX is next-generation software for the visualization and analysis of molecular structures, density maps, 3D microscopy, and associated data. It addresses challenges in the size, scope, and disparate types of data attendant with cutting-edge experimental methods, while providing advanced options for high-quality rendering (interactive ambient occlusion, reliable molecular surface calculations, etc.) and professional approaches to software design and distribution. This article highlights some specific advances in the areas of visualization and usability, performance, and extensibility. ChimeraX is free for noncommercial use and is available from http://www.rbvi.ucsf.edu/chimerax/ for Windows, Mac, and Linux.

Keywords
biomolecular visualization and analysis density maps integrative hybrid modeling interactive molecular graphics large-scale data light-sheet microscopy structural biology virtual reality
MeSH Terms
Imaging, Three-Dimensional Molecular Structure Software
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Goddard Thomas D
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
Huang Conrad C
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
Meng Elaine C
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
Pettersen Eric F
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
Couch Gregory S
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
Morris John H
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
Ferrin Thomas E ORCID
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
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Article Info
Journal
Protein science : a publication of the Protein Society
Abbr.
Protein Sci
ISSN
1469-896X
DOI
10.1002/pro.3235
Published
2018-00-00
Epub
2017-00-06
Pages
14-25
Language
English
Region
United States
NLM ID
9211750
PMCID
PMC5734306
Subset
IM
Grants
NIGMS NIH HHS · P41 GM103311 · United States
Databases
PDB
3j3q, 4d5d, 5jrg, 1ej6, 5cd4, 1t09, 2gbp, 5gmk, 4v7s
External Links
PubMed source DOI: 10.1002/pro.3235 PMC Full Text View journal details
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