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PMID: 28605774 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

GenomeHubs: simple containerized setup of a custom Ensembl database and web server for any species.

Challis RJ, Kumar S, Stevens L, Blaxter M

Abstract

http://GenomeHubs.org. As the generation and use of genomic datasets is becoming increasingly common in all areas of biology, the need for resources to collate, analyse and present data from one or more genome projects is becoming more pressing. The Ensembl platform is a powerful tool to make genome data and cross-species analyses easily accessible through a web interface and a comprehensive application programming interface. Here we introduce GenomeHubs, which provide a containerized environment to facilitate the setup and hosting of custom Ensembl genome browsers. This simplifies mirroring of existing content and import of new genomic data into the Ensembl database schema. GenomeHubs also provide a set of analysis containers to decorate imported genomes with results of standard analyses and functional annotations and support export to flat files, including EMBL format for submission of assemblies and annotations to International Nucleotide Sequence Database Collaboration.

MeSH Terms
Animals Data Warehousing/methods Databases, Nucleic Acid Genome Humans Internet Sequence Analysis, DNA/methods Web Browser
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Challis Richard J
Institute of Evolutionary Biology, The University of Edinburgh, Ashworth Laboratories, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.
Kumar Sujai
Institute of Evolutionary Biology, The University of Edinburgh, Ashworth Laboratories, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.
Stevens Lewis
Institute of Evolutionary Biology, The University of Edinburgh, Ashworth Laboratories, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.
Blaxter Mark
Institute of Evolutionary Biology, The University of Edinburgh, Ashworth Laboratories, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.
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Article Info
Journal
Database : the journal of biological databases and curation
Abbr.
Database (Oxford)
ISSN
1758-0463
Published
2017-00-01
Language
English
Region
England
NLM ID
101517697
PMCID
PMC5467552
Subset
IM
Grants
Biotechnology and Biological Sciences Research Council · BB/K020161/1 · United Kingdom
Biotechnology and Biological Sciences Research Council · BB/K019945/1 · United Kingdom
Biotechnology and Biological Sciences Research Council · BB/K020129/1 · United Kingdom
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