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PMID: 284355 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Genetic translocation in Staphylococcus aureus.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 76 ·No. 1 ·1979-01-00 ·Pages 400-4

Novick RP, Edelman I, Schwesinger MD, Gruss AD, Swanson EC, Pattee PA

Abstract

A 5.2-kilobase pair transposon, Tn551, has been found in Staphylococcus aureus, a Gram-positive bacterium. Initially detected on plasmid pI258, it undergoes rec-independent transposition to multiple chromosomal and plasmid sites, sometimes causing insertional inactivation. Unlike most other transposons, Tn551 undergoes apparently precise excision as a rule. The initial observation of Tn551 transition involved UV inactivation of the carrier plasmid; this would appear to be a general means of detecting transposable elements.

MeSH Terms
Chromosome Deletion Chromosome Mapping Drug Resistance, Microbial Erythromycin Genes Plasmids R Factors Recombination, Genetic Staphylococcus aureus/genetics Translocation, Genetic
Chemicals
Erythromycin
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Novick R P
Edelman I
Schwesinger M D
Gruss A D
Swanson E C
Pattee P A
References (12)
12 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.76.1.400
Published
1979-01-00
Pages
400-4
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC382947
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.76.1.400 PMC Full Text View journal details
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