Preparation and use of monoclonal antibodies to Na+,K+-ATPase.

Application of monoclonal antibody techniques to the study of Na+,K+-ATPase offers a unique opportunity to investigate the molecular basis of sodium potassium transport. As a highly specific tool it can help define the transport process of a molecular, epithelial, and organ level by allowing biochemical, physiological, and morphological approaches to use a single probe. With the use of proper screening procedures, a highly specific reagent can be developed with great utility for a variety of different technical approaches.