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PMID: 28305080 Published · ppublish English Journal Article

Formation of mesodermal pattern by secondary inducing interactions.

Wilhelm Roux's archives of developmental biology ·Vol. 187 ·No. 3 ·1979-09-00 ·Pages 231-244

Asahi KI, Born J, Tiedemann H, Tiedemann H

Abstract

A highly purified vegetalizing factor induces endoderm preferentially in amphibian gastrula ectoderm. After combination of this factor with less pure fractions, a high percentage of trunks and tails with notochord and somites are induced. The induction of these mesodermal tissues depends on secondary factors which may act on plasma membrane receptors of the target cells. The secondary factors are probably proteins as they are inactivated by trypsin or cellulose-bound proteinase K. They are not inactivated by thioglycolic acid.The implication of these findings for tissue determination and differentiation in normal development in relation to the anlageplan for endoderm and mesodermal tissues is discussed.

Keywords
Amphibia Mesoderm formation Secondary factors
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Asahi Ken-Ichi
Institut für Molekularbiologie und Biochemie, Freie Universität, Berlin, Arnimallee 22, D-1000, Berlin 33.
Born Jochen
Institut für Molekularbiologie und Biochemie, Freie Universität, Berlin, Arnimallee 22, D-1000, Berlin 33.
Tiedemann Heinz
Institut für Molekularbiologie und Biochemie, Freie Universität, Berlin, Arnimallee 22, D-1000, Berlin 33.
Tiedemann Hildegard
Institut für Molekularbiologie und Biochemie, Freie Universität, Berlin, Arnimallee 22, D-1000, Berlin 33.
References (18)
18 references, click to expand
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Article Info
Journal
Wilhelm Roux's archives of developmental biology
Abbr.
Wilehm Roux Arch Dev Biol
ISSN
0340-0794
DOI
10.1007/BF00848619
Published
1979-09-00
Pages
231-244
Language
English
Region
Germany
NLM ID
7508796
External Links
PubMed source DOI: 10.1007/BF00848619
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