Home LiteratureArticle Details
PMID: 28063638 Published · ppublish English Journal Article Comment

Functional Dissection of the m6A RNA Modification.

Trends in biochemical sciences ·Vol. 42 ·No. 2 ·2017-00-00 ·Pages 85-86

Huisman B, Manske G, Carney S, Kalantry S

Abstract

暂无摘要

MeSH Terms
Adenosine Humans Methylation RNA
Chemicals
RNA Adenosine
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Huisman Brooke
Department of Human Genetics, 1241 East Catherine Street, MSII 3710, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA.
Manske Gabriel
Department of Human Genetics, 1241 East Catherine Street, MSII 3710, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA.
Carney Stephen
Department of Human Genetics, 1241 East Catherine Street, MSII 3710, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA.
Kalantry Sundeep
Department of Human Genetics, 1241 East Catherine Street, MSII 3710, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA. Electronic address: Kalantry@umich.edu.
References (19)
19 references, click to expand
  1. Long nonoding RNAs in the X-inactivation center.
    Chromosome Res. 2013 Dec;21(6-7):601-14 PMID: 24297756
  2. Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.
    Cell. 2012 Jun 22;149(7):1635-46 PMID: 22608085
  3. A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing.
    Cell Rep. 2015 Jul 28;12(4):562-72 PMID: 26190105
  4. Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression.
    Nat Rev Mol Cell Biol. 2016 Dec;17 (12 ):756-770 PMID: 27780979
  5. Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.
    J Biol Chem. 2013 Nov 15;288(46):33292-302 PMID: 24100041
  6. The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus.
    Cell. 1992 Oct 30;71(3):527-42 PMID: 1423611
  7. RNA methylation by the MIS complex regulates a cell fate decision in yeast.
    PLoS Genet. 2012;8(6):e1002732 PMID: 22685417
  8. The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.
    Nature. 2015 May 14;521(7551):232-6 PMID: 25915022
  9. Using the lambdaN peptide to tether proteins to RNAs.
    Methods Mol Biol. 2004;257:135-54 PMID: 14770003
  10. Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain.
    Nat Chem Biol. 2014 Nov;10 (11):927-9 PMID: 25242552
  11. m(6)A RNA methylation promotes XIST-mediated transcriptional repression.
    Nature. 2016 Sep 15;537(7620):369-373 PMID: 27602518
  12. XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure.
    J Cell Biol. 1996 Feb;132(3):259-75 PMID: 8636206
  13. A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling.
    Genes Dev. 2003 Aug 1;17(15):1909-20 PMID: 12897056
  14. N6-methyladenosine–encoded epitranscriptomics.
    Nat Struct Mol Biol. 2016 Feb;23(2):98-102 PMID: 26840897
  15. Chromosomes. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation.
    Science. 2015 Jul 17;349(6245):null PMID: 26089354
  16. Systematic discovery of Xist RNA binding proteins.
    Cell. 2015 Apr 9;161(2):404-16 PMID: 25843628
  17. MTA is an Arabidopsis messenger RNA adenosine methylase and interacts with a homolog of a sex-specific splicing factor.
    Plant Cell. 2008 May;20(5):1278-88 PMID: 18505803
  18. Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase.
    Cell Res. 2014 Feb;24(2):177-89 PMID: 24407421
  19. The matrix protein hnRNP U is required for chromosomal localization of Xist RNA.
    Dev Cell. 2010 Sep 14;19(3):469-76 PMID: 20833368
Article Info
Journal
Trends in biochemical sciences
Abbr.
Trends Biochem Sci
ISSN
0968-0004
DOI
10.1016/j.tibs.2016.12.004
Email
kalantry@umich.edu
Published
2017-00-00
Epub
2017-00-04
Pages
85-86
Language
English
Region
England
NLM ID
7610674
PMCID
PMC5272839
Subset
IM
Grants
NIH HHS · DP2 OD008646 · United States
Corrections
CommentOn
PMID: 27602518
External Links
PubMed source DOI: 10.1016/j.tibs.2016.12.004 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2