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题目:: Lung Cancer in Women with a Family History of Cancer: The Spanish Female-specific Database WORLD07.
作者:: Isla(Dolores),Felip(Enriqueta),Viñolas(Nuria),Provencio(Mariano),Majem(Margarita),Artal(Angel),Bover(Isabel),Lianes(Pilar),DE Las Peñas(Ramón),Catot(Silvia),DE Castro(Javier),Blasco(Ana),Terrasa(Josefa),Gonzalez-Larriba(José Luis),Juan(Oscar),Dómine(Manuel),Bernabe(Reyes),Garrido(Pilar)
状态:: 发布时间2016-12-06 , 更新时间 2016-12-07
期刊:: Anticancer Res
摘要:: The WORLD07 project is a female-specific database to prospectively analyze the characteristics of Spanish women with lung cancer.,We analyzed and compared lung cancer features in women with and without a family history of cancer/lung cancer.,Two thousand and sixty women were included: 876 had a family history of cancer (lung cancer, 34%) and 886 did not, with no significant differences between groups, except for smoking status (p=0.036). We found statistically significant correlations between epidermal growth factor receptor (EGFR) mutation and smoking status in patients with a family history of cancer (r=-0.211; p<0.001) and lung cancer (r=-0.176; p<0.001). Longer median overall survival was observed in women with a family history of cancer and lung cancer.,Among Spanish women with lung cancer, a greater proportion were current smokers in those with a family history of cancer/lung cancer. There was a significant correlation between the presence of EGFR mutation and smoking.
语言:: eng
DOI:

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