Fetal to Adult Hematopoiesis with the "Flk" of a Switch.
作者:
Vanhee(Stijn),Yuan(Joan)
状态:
发布时间2016-12-02
, 更新时间 2016-12-03
期刊:
Cell Stem Cell
摘要:
Blood development relies on discrete stem and progenitor cell populations with unclear lineage relationships and distinct functional characteristics that change during ontogeny. In this issue of Cell Stem Cell, Beaudin et al. (2016) identify a hematopoietic stem cell population with fetal characteristics that is developmentally restricted yet capable of long-term multi-lineage reconstitution upon transplantation into adult recipients.