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题目:: Oncogene-directed alterations in cancer cell metabolism.
作者:: Nagarajan(Arvindhan),Malvi(Parmanand),Wajapeyee(Narendra)
状态:: 发布时间2016-11-08 , 更新时间 2016-12-02
期刊:: Trends Cancer
摘要:: Oncogenes are key drivers of tumor growth. Although several cancer-driving mechanisms have been identified, the role of oncogenes in shaping metabolic patterns in cancer cells is only beginning to be appreciated. Recent studies show that oncogenes directly regulate critical metabolic enzymes and metabolic signaling pathways. Here, we present evidence for oncogene-directed cancer metabolic regulation and discuss the importance of identifying underlying mechanisms that can be targeted for developing precision cancer therapies.
语言:: eng
DOI:

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