Under Pressure: When a Transformed Environment Pushes Cells to Malignancy.
作者:
García-Fernández(María),Méndez-Ferrer(Simón)
状态:
发布时间2016-11-04
, 更新时间 2016-11-05
期刊:
Cell Stem Cell
摘要:
Mesenchymal stem/progenitor cells (MSPCs) have recently gained attention as key elements that contribute to different stages of oncogenesis, from predisposition to disease manifestation and evolution. In this issue of Cell Stem Cell, Zambetti et al. (2016) propose a mechanism by which mutated MSPCs transform hematopoietic cells into a malignant-prone state.