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PMID: 27421661 已发表 · aheadofprint 英语

Is Autologous Salvaged Blood a Viable Option for Patient Blood Management in Oncologic Surgery?

Zaw(Aye Sandar),Bangalore Kantharajanna(Shashidhar),Kumar(Naresh)

摘要

Oncologic surgery is sometimes associated with substantial blood loss, and principles of patient blood management can be applied in the perioperative care of these patients. Although autologous salvaged blood is an option for perioperative blood conservation, it is often not used in oncologic surgery over concern of reinfusing tumor cells and thereby causing tumor dissemination. We reviewed the literature regarding safety and effectiveness of salvaged blood in oncologic surgery. Salvaged blood seems to be comparable to allogeneic blood in terms of safety. Because patients with primary or metastatic cancer are known to have circulating tumor cells in the absence of surgery, the concern of reinfusing malignant cells from the salvaged blood may be overstated. Reinfusion of salvaged blood has not been found to promote tumor dissemination or distant metastases. When used in patients with substantial blood loss, salvaged blood can be cost-effective. Intraoperative salvaged blood may be a useful adjunct to allogeneic blood resources.

关键词
Circulating tumor cells Metastasis Oncologic surgery Primary cancer Salvaged blood Tumor cells
文献信息
期刊
Transfusion medicine reviews
期刊简称
Transfus Med Rev
发表日期
0000-00-00
收录日期
2016-07-16
更新日期
2016-07-16
语言
英语
国家/地区
United States
NLM ID
8709027
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