Closing in on Mass Production of Mature Human Beta Cells.
作者:
Kieffer(Timothy J)
状态:
发布时间2016-06-04
, 更新时间 2016-06-04
期刊:
Cell Stem Cell
摘要:
Human pluripotent stem cell differentiation protocols based on mimicking developmental pathways are getting close to generating fully fledged pancreatic endocrine cells, including insulin-producing beta cells. However, challenges remain in identifying pathways to trigger the attainment of robust glucose responsiveness that occurs postnatally in beta cells.