| GeneLibs

题目:: Cancer stem cell metabolism.
作者:: Peiris-Pagès(Maria),Martinez-Outschoorn(Ubaldo E),Pestell(Richard G),Sotgia(Federica),Lisanti(Michael P)
状态:: 发布时间2016-05-25 , 更新时间 2016-10-19
期刊:: Breast Cancer Res
摘要:: Cancer is now viewed as a stem cell disease. There is still no consensus on the metabolic characteristics of cancer stem cells, with several studies indicating that they are mainly glycolytic and others pointing instead to mitochondrial metabolism as their principal source of energy. Cancer stem cells also seem to adapt their metabolism to microenvironmental changes by conveniently shifting energy production from one pathway to another, or by acquiring intermediate metabolic phenotypes. Determining the role of cancer stem cell metabolism in carcinogenesis has become a major focus in cancer research, and substantial efforts are conducted towards discovering clinical targets.
语言:: eng
DOI:

文献库文献相关信息