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题目:: [HPV DNA genotyping: A study of anogenital, head and neck and skin cancers in a population from west Algerian. HPV detection in different cancers from an Algerian population].
作者:: Nahet(Amira),Boublenza(Lamia),Hassaine(Hafida),Masdoua(Nabila),Prétet(Jean-Luc),Belglaiaa(Essaada),Mougin(Christiane)
状态:: 发布时间2016-05-16 , 更新时间 2016-05-16
期刊:: Bull Cancer
摘要:: To investigate the prevalence of human papillomaviruses (HPV) in cancers located at different sites in patients from west Algerian and collected between 2010 and 2014.,Extracted DNA from archival formaldehyde-fixed and paraffin-embedded tissues was provided from 39 anogenital cancers, 10 head and neck cancers and 36 skin cancers. The viral DNA was detected using the INNO-LiPA HPV Genotyping Extra(®) kit.,The prevalence of HPV was 100% in cervical cancers, 40% in vaginal cancers, 17% in vulvar cancers, 33% in anal cancers, 0% in tonsil and larynx cancers and 6.4% in skin squamous cell carcinoma. In cervical cancers, the most prevalent genotypes were HPV16 (52%) and HPV18 (12%) as single infection.,The overall results agree partially with literature. Extensive research is necessary to promote HPV vaccine to reduce in particular the burden of cervical cancer in Algeria.
语言:: fre
DOI:: 10.1016/j.bulcan.2016.02.016

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