The mammalian cdc2 protein kinase: mechanisms of regulation during the cell cycle.

Journal of cell science. Supplement ·Vol. 12 ·1989-00-00 ·Pages 21-7

Draetta G, Beach D

Abstract

Recent experimental evidence has demonstrated the central role of the cdc2 protein kinase in the transition from G2 to M phase in eukaryotic cells. We shall review our knowledge of the mechanisms which coordinate activation of the kinase with cell cycle-specific events in mammalian cells.

MeSH Terms

Animals CDC2 Protein Kinase Cell Cycle Enzyme Activation Fungal Proteins/metabolism Genes, Regulator Humans Mitosis Nuclear Proteins/metabolism Phosphoproteins/metabolism Protein Kinases/metabolism

Chemicals

Fungal Proteins Nuclear Proteins Phosphoproteins Protein Kinases CDC2 Protein Kinase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Draetta G

Cold Spring Harbor Laboratory, New York 11724.

Beach D

Article Info

Journal

Journal of cell science. Supplement

Abbr.

J Cell Sci Suppl

ISSN

0269-3518

DOI

10.1242/jcs.1989.supplement_12.3

Published

1989-00-00

Pages

21-7

Language

English

Region

England

NLM ID

8502898

Subset

External Links

PubMed source DOI: 10.1242/jcs.1989.supplement_12.3

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