Mammary Ductal Environment Is Necessary for Faithful Maintenance of Estrogen Signaling in ER⁺ Breast Cancer.
作者:
Haricharan(Svasti),Lei(Jonathan),Ellis(Matthew)
状态:
发布时间2016-03-16
, 更新时间 2016-10-19
期刊:
Cancer Cell
摘要:
In this issue of Cancer Cell, Sflomos et al. (2016) describe a robust preclinical animal model of ER⁺ breast cancer. The authors identify the critical role of the breast microenvironment in determining hormone response of ER⁺ breast cancer cells and in driving the luminal phenotype of breast cancer.