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PMID: 2688204 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

MHC class II invariant chains in antigen processing and presentation.

Trends in biochemical sciences ·Vol. 14 ·No. 9 ·1989-09-00 ·Pages 383-6

Koch N, Lipp J, Pessara U, Schenck K, Wraight C, Dobberstein B

Abstract

Most protein antigens cannot elicit a T-cell response unless they are processed to peptides, which are then presented to T lymphocytes by surface MHC class II molecules. Recent evidence supports an essential role of the invariant chain associated with class II MHC polypeptides in antigen processing.

MeSH Terms

Antigens/immunology Gene Expression/physiology Major Histocompatibility Complex/physiology

Chemicals

Antigens

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Koch N

Lipp J

Pessara U

Schenck K

Wraight C

Dobberstein B

Article Info

Journal

Trends in biochemical sciences

Abbr.

Trends Biochem Sci

ISSN

0968-0004

DOI

10.1016/0968-0004(89)90013-3

Published

1989-09-00

Pages

383-6

Language

English

Region

England

NLM ID

7610674

Subset

External Links

PubMed source DOI: 10.1016/0968-0004(89)90013-3 View journal details

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MHC class II invariant chains in antigen processing and presentation.

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