Time to Relax: Mechanical Stress Release Guides Stem Cell Responses.
作者:
Sommerfeld(Sven D),Elisseeff(Jennifer H)
状态:
发布时间2016-02-06
, 更新时间 2016-02-06
期刊:
Cell Stem Cell
摘要:
Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.