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PMID: 2674892 Published · ppublish English Journal Article

Cromakalim (BRL 34915) and diazoxide activate ATP-regulated potassium channels in insulin-secreting cells.

Pflugers Archiv : European journal of physiology ·Vol. 414 Suppl 1 ·1989-00-00 ·Pages S154-5

Dunne MJ, Yule DI, Gallacher DV, Petersen OH

Abstract

暂无摘要

MeSH Terms
Adenosine Triphosphate/physiology Animals Benzopyrans/pharmacology Cell Line Cromakalim Diazoxide/pharmacology Insulin/metabolism Insulin Secretion Islets of Langerhans/drug effects,metabolism Potassium Channels/drug effects Pyrroles/pharmacology Vasodilator Agents/pharmacology
Chemicals
Benzopyrans Insulin Potassium Channels Pyrroles Vasodilator Agents Cromakalim Adenosine Triphosphate Diazoxide
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Dunne M J
M.R.C. Secretory Control Research Group, University of Liverpool, Great Britain.
Yule D I
Gallacher D V
Petersen O H
References (6)
6 references, click to expand
  1. Interaction of diazoxide, tolbutamide and ATP4- on nucleotide-dependent K+ channels in an insulin-secreting cell line.
    J Membr Biol. 1987;99(3):215-24 PMID: 2447283
  2. Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells.
    Pflugers Arch. 1986 Nov;407(5):493-9 PMID: 2431383
  3. The potassium channel opener cromakalim (BRL 34915) activates ATP-dependent K+ channels in isolated cardiac myocytes.
    Biochem Biophys Res Commun. 1988 Jul 29;154(2):620-5 PMID: 2456760
  4. Electrophysiology of the pancreas.
    Physiol Rev. 1987 Jul;67(3):1054-116 PMID: 2440063
  5. Signal transduction in insulin secretion: comparison between fuel stimuli and receptor agonists.
    Ann N Y Acad Sci. 1986;488:317-33 PMID: 3107454
  6. Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein.
    Br J Pharmacol. 1986 May;88(1):103-11 PMID: 3708211
Article Info
Journal
Pflugers Archiv : European journal of physiology
Abbr.
Pflugers Arch
ISSN
0031-6768
DOI
10.1007/BF00582279
Published
1989-00-00
Pages
S154-5
Language
English
Region
Germany
NLM ID
0154720
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00582279 View journal details
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