The polymerase chain reaction.

Trends in genetics : TIG ·Vol. 5 ·No. 6 ·1989-06-00 ·Pages 185-9

White TJ, Arnheim N, Erlich HA

Abstract

The polymerase chain reaction (PCR) is a powerful new method for 'in vitro cloning'. It can selectively amplify a single molecule of template DNA several millionfold in a few hours and has made possible new approaches to problems in molecular genetics, evolutionary biology, and development.

MeSH Terms

Biological Evolution Cell Differentiation Cloning, Molecular/methods DNA-Directed DNA Polymerase/metabolism Forensic Medicine Genetics Humans Nucleic Acid Amplification Techniques Taq Polymerase

Chemicals

Taq Polymerase DNA-Directed DNA Polymerase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

White T J

Arnheim N

Erlich H A

Article Info

Journal

Trends in genetics : TIG

Abbr.

Trends Genet

ISSN

0168-9525

DOI

10.1016/0168-9525(89)90073-5

Published

1989-06-00

Pages

185-9

Language

English

Region

England

NLM ID

8507085

Subset

External Links

PubMed source DOI: 10.1016/0168-9525(89)90073-5 View journal details

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The polymerase chain reaction.

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