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题目:: Chemoprevention trials of GI cancers in Asia.
作者:: Li(James Weiquan),Tan(Malcolm Teck Kiang),Ang(Tiing Leong),Teo(Eng Kiong)
状态:: 发布时间2015-12-15 , 更新时间 2015-12-15
期刊:: Best Pract Res Clin Gastroenterol
摘要:: Cancers are among the leading causes of morbidity and mortality worldwide, with gastrointestinal (GI) luminal cancers accounting for a large proportion of cancer incidence. Chemoprevention of GI luminal cancers is important to reduce this cancer burden. Screening for and eradication of Helicobacter pylori (H. pylori) in areas with high gastric cancer incidence is a safe and effective strategy to decrease the incidence of gastric cancer. Eradication of H. pylori also seems to be effective in preventing metachronous cancer development after endoscopic resection of early gastric cancer. For the average risk individual, COX inhibitors may have a role in reducing the incidence of adenoma formation as well as colorectal cancer, bearing in mind its inherent risks. There is currently insufficient evidence to recommend a chemoprevention agent against esophageal and small intestine cancer.
语言:: eng
DOI:: 10.1016/j.bpg.2015.09.014

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