More Frequent than Desired: Midgut Stem Cell Somatic Mutations.
作者:
Li(Qi),Ip(Y Tony)
状态:
发布时间2015-12-07
, 更新时间 2016-10-19
期刊:
Cell Stem Cell
摘要:
The accumulation of somatic mutations in adult stem cells contributes to the decline of tissue functions and cancer initiation. In this issue of Cell Stem Cell, Siudeja et al. (2015) investigate the rate and mechanism of naturally occurring mutations in Drosophila midgut intestinal stem cells during aging and find high-frequency mutations arising from multiple mechanisms.