Heparin-induced thrombocytopenia.

Heparin-induced thrombocytopenia is the most important idiosyncratic drug-induced thrombocytopenia because of its high frequency and association with arterial thrombosis. Recent evidence implicates heparin-IgG immune complexes in the pathogenesis of this disorder. New developments such as a diagnostic test for heparin-induced thrombocytopenia and current treatment recommendations are reviewed.