Do SNARE Protein Isoforms Determine Fusion Pore Characteristics?

The Journal of neuroscience : the official journal of the Society for Neuroscience ·Vol. 35 ·No. 33 ·2015-08-19 ·Pages 11459-61

van Keimpema L, Kroon T

Abstract

暂无摘要

MeSH Terms

Animals Cell Membrane/metabolism Humans Membrane Fusion/physiology Secretory Vesicles/genetics Vesicle-Associated Membrane Protein 2/chemistry,metabolism

Chemicals

Vesicle-Associated Membrane Protein 2

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

van Keimpema Linda ORCID

Sylics (Synaptologics B.V.), 1008 BA, Amsterdam, The Netherlands, and Departments of Functional Genomics and l.van.keimpema@vu.nl.

Kroon Tim ORCID

Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, VU University, 1081 HV, Amsterdam, The Netherlands.

References (17)

17 references, click to expand

Dendritic integration of excitatory synaptic input.
Nat Rev Neurosci. 2000 Dec;1(3):181-90 PMID: 11257906
Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis.
Science. 2004 Apr 9;304(5668):289-92 PMID: 15016962
v-SNAREs control exocytosis of vesicles from priming to fusion.
EMBO J. 2005 Jun 15;24(12):2114-26 PMID: 15920476
Fusion pores and fusion machines in Ca2+-triggered exocytosis.
Annu Rev Biophys Biomol Struct. 2006;35:135-60 PMID: 16689631
The fusion pores of Ca2+ -triggered exocytosis.
Nat Struct Mol Biol. 2008 Jul;15(7):684-9 PMID: 18596819
Transmembrane-domain determinants for SNARE-mediated membrane fusion.
J Cell Sci. 2010 Jul 15;123(Pt 14):2473-80 PMID: 20571052
The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices--guilty as charged?
Annu Rev Cell Dev Biol. 2012;28:279-308 PMID: 23057743
Molecular machines governing exocytosis of synaptic vesicles.
Nature. 2012 Oct 11;490(7419):201-7 PMID: 23060190
Distinct initial SNARE configurations underlying the diversity of exocytosis.
Physiol Rev. 2012 Oct;92(4):1915-64 PMID: 23073634
Perspectives on kiss-and-run: role in exocytosis, endocytosis, and neurotransmission.
Annu Rev Physiol. 2013;75:393-422 PMID: 23245563
VAMP4 is required to maintain the ribbon structure of the Golgi apparatus.
Mol Cell Biochem. 2013 Aug;380(1-2):11-21 PMID: 23677696
Importance of polarity of the α4-α5 loop residue-Asn(166) in the pore-forming domain of the Bacillus thuringiensis Cry4Ba toxin: implications for ion permeation and pore opening.
Biochim Biophys Acta. 2014 Jan;1838(1 Pt B):319-27 PMID: 24120447
Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles.
Nat Commun. 2014;5:3356 PMID: 24561832
Synaptobrevin 1 mediates vesicle priming and evoked release in a subpopulation of hippocampal neurons.
J Neurophysiol. 2014 Sep 15;112(6):1559-65 PMID: 24944211
How could SNARE proteins open a fusion pore?
Physiology (Bethesda). 2014 Jul;29(4):278-85 PMID: 24985331
A structural role for the synaptobrevin 2 transmembrane domain in dense-core vesicle fusion pores.
J Neurosci. 2015 Apr 8;35(14):5772-80 PMID: 25855187
Astrocyte VAMP3 vesicles undergo Ca2+ -independent cycling and modulate glutamate transporter trafficking.
J Physiol. 2015 Jul 1;593(13):2807-32 PMID: 25864578

Article Info

Journal

The Journal of neuroscience : the official journal of the Society for Neuroscience

Abbr.

J Neurosci

ISSN

1529-2401

DOI

10.1523/JNEUROSCI.2087-15.2015

l.van.keimpema@vu.nl

Published

2015-08-19

Pages

11459-61

Language

English

Region

United States

NLM ID

8102140

PMCID

PMC6605234

Subset

Corrections

CommentOn

PMID: 25855187

External Links

PubMed source DOI: 10.1523/JNEUROSCI.2087-15.2015 PMC Full Text View journal details

Analysis Services

Do SNARE Protein Isoforms Determine Fusion Pore Characteristics?

Contact

WeChat Official Account