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题目:: Post-diagnostic oral bisphosphonate use and colorectal cancer mortality: a population-based cohort study within the UK Clinical Practice Research Datalink.
作者:: Hicks(B M),Murray(L J),Hughes(C),Cardwell(C R)
状态:: 发布时间2015-07-01 , 更新时间 2016-11-25
期刊:: Br J Cancer
摘要:: We conducted the first study to investigate post-diagnostic oral bisphosphonates use and colorectal cancer-specific mortality.,Colorectal cancer patients were identified from the National Cancer Data Repository (1998-2007) and linked to the UK Clinical Practice Research Datalink, providing prescription records, and Office of National Statistics mortality data. Time-dependent Cox regression models investigated colorectal cancer-specific mortality in post-diagnostic bisphosphonate users.,Overall, in 4791 colorectal cancer patients, there was no evidence of an association between bisphosphonate use and colorectal cancer-specific mortality (adjusted hazard ratio=1.11; 95% confidence interval 0.80, 1.54) or with drug frequency or type.,In this novel population-based cohort study, post-diagnostic bisphosphonate use was not associated with longer rates of colorectal cancer survival.
语言:: eng
DOI:

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