The effect of cyanide on the K-current in guinea-pig ventricular myocytes.

Basic research in cardiology ·Vol. 80 Suppl 1 ·1985-00-00 ·Pages 93-6

Van der Heyden G, Vereecke J, Carmeliet E

Abstract

The mechanism of the shortening of the cardiac action potential by cyanide was studied in guinea-pig ventricular myocytes using a two micro-electrode voltage clamp technique. It is shown that the shortening can be counteracted by glucose and is due to a marked increase in K conductance.

MeSH Terms

Animals Blood Glucose/metabolism Cells, Cultured Cyanides/pharmacology Electrocardiography Energy Metabolism/drug effects Guinea Pigs Heart Ventricles/drug effects Ion Channels/drug effects,metabolism Myocardium/cytology Oxygen/pharmacology Oxygen Consumption/drug effects Potassium/metabolism Sodium Cyanide/pharmacology

Chemicals

Blood Glucose Cyanides Ion Channels Sodium Cyanide Potassium Oxygen

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Van der Heyden G

Vereecke J

Carmeliet E

Article Info

Journal

Basic research in cardiology

Abbr.

Basic Res Cardiol

ISSN

0300-8428

DOI

10.1007/978-3-662-11041-6_18

Published

1985-00-00

Pages

93-6

Language

English

Region

Germany

NLM ID

0360342

Subset

External Links

PubMed source DOI: 10.1007/978-3-662-11041-6_18 View journal details

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The effect of cyanide on the K-current in guinea-pig ventricular myocytes.

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