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PMID: 2578627 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors.

Nature ·Vol. 313 ·No. 6003 ·1985-00-00 ·Pages 552-7

Konarska MM, Grabowski PJ, Padgett RA, Sharp PA

Abstract

The branch site of lariat RNAs produced during the splicing of the first two late leader exons of adenovirus-2 has a structure of (formula; see text) There is a distinct complementarity between sequences preceding the adenosine at the branch site and the 5' terminus of the intervening sequence.

MeSH Terms

Adenoviruses, Human/genetics Base Sequence HeLa Cells/metabolism Humans Nucleic Acid Conformation Nucleic Acid Precursors/analysis Oligonucleotides/analysis RNA/analysis RNA Precursors RNA Splicing RNA, Messenger/analysis RNA, Viral/analysis Ribonuclease, Pancreatic Ribonucleoproteins/metabolism Ribonucleoproteins, Small Nuclear

Chemicals

Nucleic Acid Precursors Oligonucleotides RNA Precursors RNA, Messenger RNA, Viral Ribonucleoproteins Ribonucleoproteins, Small Nuclear RNA Ribonuclease, Pancreatic

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Konarska M M

Grabowski P J

Padgett R A

Sharp P A

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/313552a0

Published

1985-00-00

Pages

552-7

Language

English

Region

England

NLM ID

0410462

Subset

Grants

NCI NIH HHS · P01-CA14051 · United States

NCI NIH HHS · P01-CA26717 · United States

NIGMS NIH HHS · R01-GM32467 · United States

External Links

PubMed source DOI: 10.1038/313552a0 View journal details

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Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors.

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