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题目:: Functions and Mechanisms of Long Noncoding RNAs in Ovarian Cancer.
作者:: Ren(Chengcheng),Li(Xiaobo),Wang(Tianzhen),Wang(Guangyu),Zhao(Ci),Liang(Tian),Zhu(Yuanyuan),Li(Minghui),Yang(Chao),Zhao(Yunlong),Zhang(Guang-mei)
状态:: 发布时间2015-04-23 , 更新时间 2015-04-23
期刊:: Int J Gynecol Cancer
摘要:: Long noncoding RNAs (lncRNAs) are longer than 200-nucleotide, noncoding transcripts in length, have a variety of biological functions, and are closely associated with tumor development. Ovarian cancer, as 1 of the 3 common gynecological malignancies, is the leading cause of death in women with gynecological malignant tumor. In this study, a review of the literature found that lncRNAs H19, LSINCT5, and XIST have a close relationship to the development of ovarian cancer occurrence, growth, invasion, and metastasis, and they can promote ovarian cancer cell proliferation. Hence, in this article, the progress of above-mentioned 3 kinds of lncRNAs in ovarian cancer was reviewed and designed to help in the diagnosis, treatment, and prognosis of ovarian cancer.
语言:: eng
DOI:: 10.1097/IGC.0000000000000413

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