Hostile takeover: glioma stem cells recruit TAMs to support tumor progression.
作者:
Shi(Yu),Ping(Yi-fang),Zhang(Xia),Bian(Xiu-wu)
状态:
发布时间2015-03-09
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
The dynamic interaction between cancer cells and immune cells is a critical concern for developing effective tumor immunotherapies. In a recent issue of Nature Cell Biology, Zhou et al. (2015) report that glioma stem cells secrete Periostin (POSTN), which recruits tumor-associated macrophages (TAMs) and supports the tumor-promoting M2 subtype.