Charting a map through the cellular reprogramming landscape.
作者:
Wen(Lu),Tang(Fuchou)
状态:
发布时间2015-03-09
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Analysis of the molecular mechanisms underlying somatic cell reprogramming into iPSCs is hampered by low efficiency of conversion and resulting cellular heterogeneity. In this issue of Cell Stem Cell, Zunder et al. (2015) utilize mass cytometry to perform high-throughput, single-cell analyses and provide a detailed molecular roadmap of the reprogramming process.