Treatment of right-sided Staphylococcus aureus endocarditis in intravenous drug users with ciprofloxacin and rifampicin.

Lancet (London, England) ·Vol. 2 ·No. 8671 ·1989-11-04 ·Pages 1071-3

Dworkin RJ, Lee BL, Sande MA, Chambers HF

Abstract

A combination of ciprofloxacin (intravenous then oral) and oral rifampicin was tested in 14 intravenous drug users with right-sided Staphylococcus aureus endocarditis. All 10 patients who completed therapy were cured based on resolution of symptoms and negative blood cultures at 4 weeks post therapy.

MeSH Terms

Adult Ciprofloxacin/administration & dosage,therapeutic use Drug Administration Schedule Drug Therapy, Combination Echocardiography Endocarditis, Bacterial/drug therapy,etiology,microbiology Female Follow-Up Studies Humans Male Pilot Projects Rifampin/administration & dosage,therapeutic use Staphylococcal Infections/drug therapy,etiology,microbiology Substance Abuse, Intravenous/complications

Chemicals

Ciprofloxacin Rifampin

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Dworkin R J

Department of Medicine, University of California, San Francisco.

Lee B L

Sande M A

Chambers H F

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/s0140-6736(89)91083-0

Published

1989-11-04

Pages

1071-3

Language

English

Region

England

NLM ID

2985213R

Subset

Corrections

CommentIn

PMID: 2574800

External Links

PubMed source DOI: 10.1016/s0140-6736(89)91083-0 View journal details

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Treatment of right-sided Staphylococcus aureus endocarditis in intravenous drug users with ciprofloxacin and rifampicin.

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