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题目:: Pancreatic cancer-associated diabetes is an "exosomopathy".
作者:: Korc(Murray)
状态:: 发布时间2015-04-02 , 更新时间 2016-10-19
期刊:: Clin Cancer Res
摘要:: Diabetes may be a consequence of pancreatic cancer, preceding cancer diagnosis. The underlying mechanism is the release of exosomes delivering adrenomedullin to β cells, inducing endoplasmic reticulum stress and perturbations in the unfolded protein response, leading to β-cell dysfunction and death. This knowledge could lead to improved diagnostic strategies for pancreatic cancer.
语言:: eng
DOI:

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