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PMID: 2558854 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19.

Cytogenetics and cell genetics ·Vol. 52 ·No. 1-2 ·1989-00-00 ·Pages 11-4

Mohrenweiser HW, Carrano AV, Fertitta A, Perry B, Thompson LH, Tucker JD, Weber CA

Abstract

Three DNA repair genes, ERCC1, ERCC2, and XRCC1, have been regionally mapped on human chromosome 19. ERCC2 and XRCC1 have been assigned to bands q13.2----q13.3 by in situ hybridization using fluorescently-labeled cosmid probes. ERCC1 and ERCC2 have been found to be separated by less than 250 kb by large fragment restriction enzyme site mapping.

MeSH Terms

Blotting, Southern Chromosome Mapping Chromosomes, Human, Pair 19 DNA DNA Probes DNA Repair/genetics DNA Restriction Enzymes Electrophoresis, Agar Gel Female Genetic Linkage Humans Nucleic Acid Hybridization

Chemicals

DNA Probes DNA DNA Restriction Enzymes

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Mohrenweiser H W

Biomedical Sciences Division, Lawrence Livermore National Laboratory, Livermore, CA 94550.

Carrano A V

Fertitta A

Perry B

Thompson L H

Tucker J D

Weber C A

Article Info

Journal

Cytogenetics and cell genetics

Abbr.

Cytogenet Cell Genet

ISSN

0301-0171

DOI

10.1159/000132829

Published

1989-00-00

Pages

11-4

Language

English

Region

Switzerland

NLM ID

0367735

Subset

External Links

PubMed source DOI: 10.1159/000132829

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Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19.

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