The gene for human muscle-specific phosphoglycerate mutase, PGAM2, mapped to chromosome 7 by polymerase chain reaction.

Genomics ·Vol. 5 ·No. 4 ·1989-11-00 ·Pages 948-51

Edwards YH, Sakoda S, Schon E, Povey S

Abstract

The gene for the human muscle-specific phosphoglycerate mutase, PGAM2, has been mapped to chromosome 7 using the polymerase chain reaction to specifically amplify the human PGAM2 sequence in rodent/human hybrid DNA. This assignment shows that the PGAM2 is not syntenic with the nonmuscle form of PGAM1 (B) which has been located to chromosome 10.

MeSH Terms

Animals Base Sequence Blotting, Southern Chromosome Mapping Chromosomes, Human, Pair 7 Gene Amplification Genes Humans Hybrid Cells Muscles/enzymology Oligodeoxyribonucleotides Phosphoglycerate Mutase/genetics Phosphotransferases/genetics Polymerase Chain Reaction

Chemicals

Oligodeoxyribonucleotides Phosphotransferases Phosphoglycerate Mutase

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Edwards Y H

MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London, England.

Sakoda S

Schon E

Povey S

Article Info

Journal

Genomics

Abbr.

Genomics

ISSN

0888-7543

DOI

10.1016/0888-7543(89)90140-7

Published

1989-11-00

Pages

948-51

Language

English

Region

United States

NLM ID

8800135

Subset

External Links

PubMed source DOI: 10.1016/0888-7543(89)90140-7 View journal details

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The gene for human muscle-specific phosphoglycerate mutase, PGAM2, mapped to chromosome 7 by polymerase chain reaction.

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