Different clinical effects upon separate inhibition of coexisting EGFR and PI3KCA mutations in a lung adenocarcinoma patient.

Lung cancer (Amsterdam, Netherlands) ·第 87 卷 ·第 2 期 ·2016-02-24

Tiseo Marcello, Bersanelli Melissa, Perrone Federica, Tamborini Elena, Settanni Giulio, Busico Adele, Rossi Giulio, Ardizzoni Andrea, Pelosi Giuseppe

摘要

We present a very interesting case of lung adenocarcinoma carrying an uncommon EGFR exon 19 insertion with concomitant PIK3CA mutation showing dramatic and persisting improvement upon erlotinib therapy, after progression during PI3K inhibitor.

关键词

EGFR Erlotinib Gene mutations NSCLC PI3K inhibitor PI3KCA

文献信息

期刊

Lung cancer (Amsterdam, Netherlands)

期刊简称

Lung Cancer

ISSN

0169-5002

DOI

10.1016/j.lungcan.2014.12.008

发表日期

2016-02-24

收录日期

2015-01-19

更新日期

2015-01-19

语言

英语

国家/地区

Ireland

NLM ID

8800805

外部链接

PubMed 原文 DOI: 10.1016/j.lungcan.2014.12.008 查看期刊详情

分析服务

Different clinical effects upon separate inhibition of coexisting EGFR and PI3KCA mutations in a lung adenocarcinoma patient.

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