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PMID: 2553680 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The structurally related exbB and tolQ genes are interchangeable in conferring tonB-dependent colicin, bacteriophage, and albomycin sensitivity.

Journal of bacteriology ·Vol. 171 ·No. 11 ·1989-11-00 ·Pages 6387-90

Braun V

Abstract

Double exbB tolQ mutants of Escherichia coli were completely resistant to bacteriophages T1 and phi 80, in contrast to strains with exbB or tolQ mutations, which were sensitive. Cells carrying mutations in exbB were partially tolerant to colicins B, D, and M and became fully tolerant by the introduction of tolQ mutations. This suggested involvement of both exbB and tolQ in tonB-dependent uptake.

MeSH Terms
Anti-Bacterial Agents/pharmacology Bacterial Proteins/genetics Colicins/pharmacology Coliphages/genetics Escherichia coli/drug effects,genetics,physiology Escherichia coli Proteins Ferrichrome/pharmacology Genes, Bacterial Mutation T-Phages/genetics
Chemicals
Anti-Bacterial Agents Bacterial Proteins Colicins Escherichia coli Proteins ExbB protein, E coli tolQ protein, E coli Ferrichrome albomycin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Braun V
Mikrobiologie II, Universität Tübingen, Federal Republic of Germany.
References (17)
17 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.171.11.6387-6390.1989
Published
1989-11-00
Pages
6387-90
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC210519
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.171.11.6387-6390.1989 PMC Full Text View journal details
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