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题目:
Epigenetic noise fuels cancer evolution.
作者:
Swanton(Charles),Beck(Stephan)
状态:
发布时间2014-12-10 , 更新时间 2014-12-10
期刊:
Cancer Cell
摘要:
Cancer is a disease of the genome and the epigenome. Previous studies have shown that genomic changes such as mutations, copy number variation, and genomic rearrangements drive cancer evolution. In this issue of Cancer Cell, Landau and colleagues add epigenomic changes, specifically locally disordered DNA methylation, to cancer's evolutionary trajectory.
语言:
eng
DOI:
10.1016/j.ccell.2014.11.003

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