Retro-secretion of recombinant proteins.

Nature ·Vol. 340 ·No. 6231 ·1989-07-27 ·Pages 323-4

Wills JW

Abstract

The retroviral Gag protein can be used to package recombinant proteins produced by mammalian cell cultures. Protein products can then be isolated easily from the recombinant virions.

MeSH Terms

Avian Sarcoma Viruses/genetics Biotechnology/methods Cytochrome c Group/genetics Cytochromes c Gene Products, gag Glycoproteins/isolation & purification Recombinant Fusion Proteins/genetics Recombinant Proteins/genetics,isolation & purification Retroviridae Proteins/genetics Saccharomyces cerevisiae/genetics Saccharomyces cerevisiae Proteins

Chemicals

CYC1 protein, S cerevisiae Cytochrome c Group Gene Products, gag Glycoproteins Recombinant Fusion Proteins Recombinant Proteins Retroviridae Proteins Saccharomyces cerevisiae Proteins Cytochromes c

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Wills J W

Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center--Shreveport 71130.

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/340323a0

Published

1989-07-27

Pages

323-4

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/340323a0 View journal details

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Retro-secretion of recombinant proteins.

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