Electron microscopic studies of endocrine hyperplasia in duodenal adenomas in familial adenomatous polyposis.
作者:
Mogensen(A M),Hage(E),Bülow(S)
状态:
发布时间1989-05-26
, 更新时间 2004-11-17
期刊:
Virchows Arch A Pathol Anat Histopathol
摘要:
Electron microscopical studies on endocrine cell hyperplasia of duodenal adenomas from five patients with familial adenomatous polyposis were performed. All the endocrine cell types normally found in the duodenal mucosa were identified. A constant feature was proliferation of duodenal-enterochromaffin cells but an increase in the number of all other endocrine cell types apart from pyloric-gastrin cells and somatostatin cells, was also observed. Certain types of intestinal endocrine cells (the intestinal enterochromaffin cell and the glicentin cell) are rare cells in the normal duodenal mucosa. The finding of these cells may indicate increased biological aggressivity.