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PMID: 2539528 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Investigation of varicella-zoster virus infection of lymphocytes by in situ hybridization.

Journal of virology ·Vol. 63 ·No. 5 ·1989-05-00 ·Pages 2392-5

Koropchak CM, Solem SM, Diaz PS, Arvin AM

Abstract

Peripheral blood mononuclear cells harboring viral gene sequences were detected during primary varicella-zoster virus (VZV) infection of the human host and the strain 2 guinea pig by in situ hybridization with a 3H-labeled VZV DNA probe. Activated T lymphocytes were permissive for VZV infection at low frequency in vitro.

MeSH Terms
Animals DNA Probes DNA, Viral/analysis Guinea Pigs Herpes Zoster/diagnosis Herpesvirus 3, Human/genetics Humans Lymphocyte Activation Lymphocytes/microbiology Nucleic Acid Hybridization Species Specificity
Chemicals
DNA Probes DNA, Viral
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Koropchak C M
Department of Pediatrics, Stanford University School of Medicine, California 94305.
Solem S M
Diaz P S
Arvin A M
References (21)
21 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.63.5.2392-2395.1989
Published
1989-05-00
Pages
2392-5
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC250665
Subset
IM
Grants
NIAID NIH HHS · AI 00624 · United States
NIAID NIH HHS · AI 20459 · United States
NIAID NIH HHS · AI 22280 · United States
External Links
PubMed source DOI: 10.1128/JVI.63.5.2392-2395.1989 PMC Full Text View journal details
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