Cellular differences in protein synthesis regulate tissue homeostasis.
作者:
Buszczak(Michael),Signer(Robert A J),Morrison(Sean J)
状态:
发布时间2014-10-11
, 更新时间 2016-11-22
期刊:
Cell
摘要:
Although sometimes considered a "house-keeping" function, multiple aspects of protein synthesis are regulated differently among somatic cells, including stem cells, and can be modulated in a cell-type-specific manner. These differences are required to establish and maintain differences in cell identity, cell function, tissue homeostasis, and tumor suppression.