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PMID: 2530177 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Spontaneous switching of the sucrose-promoted colony phenotype in Streptococcus sanguis.

Infection and immunity ·Vol. 57 ·No. 12 ·1989-12-00 ·Pages 3945-8

Tardif G, Sulavik MC, Jones GW, Clewell DB

Abstract

Streptococcus sanguis on media containing 3% sucrose gives rise to characteristic hard cohesive colonies (designated Spp+). Populations of Spp+ bacteria (strain Challis) on sucrose media switch to a soft noncohesive phenotype (designated Spp-) at a frequency of 10(-4) to 10(-3). Spp- bacteria switch back to Spp+ bacteria at a similar frequency. Successive rounds of Spp variation were observed. The Spp phenotypic switch was associated with changes in extracellular glucosyltransferase activity.

MeSH Terms
Glucosyltransferases/metabolism Hexosyltransferases/metabolism Streptococcus sanguis/cytology,enzymology Sucrose/metabolism
Chemicals
Sucrose Glucosyltransferases Hexosyltransferases inulosucrase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Tardif G
Department of Microbiology and Immunology, School of Medicine, University of Michigan, Ann Arbor 48109-0402.
Sulavik M C
Jones G W
Clewell D B
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.57.12.3945-3948.1989
Published
1989-12-00
Pages
3945-8
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC259931
Subset
IM
Grants
NIDCR NIH HHS · DE02731 · United States
External Links
PubMed source DOI: 10.1128/iai.57.12.3945-3948.1989 PMC Full Text View journal details
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