Reinventing the neural crest: direct reprogramming makes iNCCs.
作者:
Varum(Sandra),Sommer(Lukas)
状态:
发布时间2014-10-04
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Aberrant neural crest (NC) development is at the origin of many congenital diseases. Given the limitations in human NC cell isolation and expansion, the development of new strategies for NC generation is crucial. In this issue of Cell Stem Cell, Kim et al. (2014) report the direct reprogramming of postnatal fibroblasts into multipotent NC cells.