Specificity of the dexamethasone-induced steroid receptor in Tetrahymena.

Experientia ·Vol. 45 ·No. 2 ·1989-02-15 ·Pages 174-5

Csaba G, Inczefi-Gonda A

Abstract

The dexamethasone-induced steroid receptor of Tetrahymena pyriformis specifically binds triamcinolone, which is itself a fluorinated glucocorticoid. It also binds dihydro-epi-androsterone (DHEA) but no or very little testosterone, digoxin or ouabain. It follows that the specificity of the induced steroid receptor of Tetrahymena may only partially be comparable with that of the mammalian steroid receptor.

MeSH Terms

Animals Dehydroepiandrosterone/metabolism Dexamethasone/pharmacology Digoxin/metabolism Ouabain/metabolism Receptors, Steroid/drug effects,metabolism Testosterone/metabolism Tetrahymena pyriformis/metabolism Triamcinolone/metabolism

Chemicals

Receptors, Steroid Triamcinolone Testosterone Dehydroepiandrosterone Ouabain Digoxin Dexamethasone

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Csaba G

Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.

Inczefi-Gonda A

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14 references, click to expand

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Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF01954865

Published

1989-02-15

Pages

174-5

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF01954865

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Specificity of the dexamethasone-induced steroid receptor in Tetrahymena.

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