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题目:: Metabolic asymmetry in cancer: a "balancing act" that promotes tumor growth.
作者:: Martinez-Outschoorn(Ubaldo E),Sotgia(Federica),Lisanti(Michael P)
状态:: 发布时间2014-07-16 , 更新时间 2016-11-25
期刊:: Cancer Cell
摘要:: Profound metabolic differences between cancer cells and fibroblasts promote tumorigenesis. A study by Valencia and colleagues in this issue of Cancer Cell supports this assertion. They observed that metabolic asymmetry in prostate tumors drives aggressive disease with high p62 in anabolic cancer cells, but loss of p62 in catabolic fibroblasts.
语言:: eng
DOI:: 10.1016/j.ccr.2014.06.021

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