Prostate cancer cells alter the nature of their calcium influx to promote growth and acquire apoptotic resistance.
作者:
Monteith(Gregory R)
状态:
发布时间2014-07-16
, 更新时间 2016-11-25
期刊:
Cancer Cell
摘要:
In this issue of Cancer Cell, Dubois and colleagues report a remodeling of calcium influx in prostate cancer cells. Prostate cancer cells can undergo an oncogenic switch from a calcium influx pathway capable of inducing apoptosis involving ORAI1 channels to a pro-proliferative calcium influx pathway involving ORAI1/3 heteromeric channels.