Neural stem cell quiescence comes to an un-sticky end.
作者:
Long(Katherine R),Ffrench-Constant(Charles)
状态:
发布时间2014-07-01
, 更新时间 2016-11-22
期刊:
Nat Cell Biol
摘要:
Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.